Blood Related Pathogens Panel

BACKGROUND

Understanding Blood Related Pathogens

Blood related pathogens refer to microorganisms that can persist long-term in the human bloodstream and cause infectious diseases, covering viruses, bacteria, parasites, and other major types. Their transmission routes include blood transfusion and blood product infusion, shared contaminated syringes, mother-to-child transmission, and close contact with an infected person’s body fluids. Infections often lead to chronic liver disease, immunodeficiency, sepsis, and other severe outcomes, and some of these diseases have extremely high mortality.

iGeneTech employs the proprietary TargetSeq® liquid-phase probe hybrid capture technology and bespoke microbial probe design to address critical challenges such as viral mutation monitoring, low-abundance viral sample detection, and host tracing, and now offers multiple whole-genome assay kits for blood related pathogens.

COMPREHENSIVE BLOODSTREAM PATHOGEN PANELS

Comprehensive Bloodstream Pathogen Detection Panels

Selected panels covering bloodborne viruses and bacterial threats, with transparent reference metrics for each design.

Product Name	English Name	Abbreviation	Taxonomy ID	Reference Genome Size	Reference Sequence Number	Number Of Probe
Hepacivirus Hominis Panel	Hepacivirus hominis	HCV	3052230	9.4 kb	1132	75136
Lyssavirus Panel	Lyssavirus	LYSV	11286	11.9 kb	3469	43985
Clostridium Botulinum Panel	Clostridium botulinum	C. botulinum	1491	3.7 Mb	74	645053
Neisseria Meningitidis Panel	Neisseria meningitidis	N. meningitidis	487	2.1 Mb	144	122125
Hepatitis A & E Virus Panel	Hepatitis A virus	HAV	12092	7.5 kb	142	120325
Hepatitis A & E Virus Panel	Orthohepevirinae	/	2946639	7.2 kb	583	120325
Hepatitis Delta Virus Panel	Hepatitis delta virus	HDV	12475	1.7 kb	765	6871

MEASURED PERFORMANCE

Measured Performance

Captured coverage maps for representative blood-borne pathogen panels.

Neisseria meningitidis panel coverage metrics

CATALOG NUMBERS & KIT SIZES

Catalog Numbers & Kit Sizes

Catalog SKUs for the highlighted bloodstream pathogen panels.

Product Name	16 rxn	96 rxn
Hepacivirus Hominis Panel	PH2003051	PH2003052
Lyssavirus Panel	PH2006931	PH2006932
Clostridium Botulinum Panel	PH2010931	PH2010932
Neisseria Meningitidis Panel	PH2010921	PH2010922
Hepatitis A & E Virus Panel	PH2011651	PH2011652
Hepatitis Delta Virus Panel	PH2014261	PH2014262

PANEL OVERVIEW

Comprehensive Bloodstream Pathogen Detection

The Blood Related Pathogens Panel enables simultaneous detection and identification of over 70 bloodstream pathogens from a single sample, covering bacteria, viruses, fungi, and parasites that cause life-threatening bloodstream infections.

Bloodstream Infection Focus

Targets pathogens commonly causing bacteremia, sepsis, and other bloodstream infections

Broad Pathogen Coverage

Detects bacteria, viruses, fungi, and parasites from blood samples

Full-Genome Analysis

Complete genome sequencing enables strain typing and resistance gene detection

Rapid Diagnosis

Fast workflow delivers results within 24 hours for timely sepsis management

KEY ADVANTAGES

Why Choose OmniCapture Blood Panel

Advanced technology for bloodstream pathogen detection

Comprehensive Coverage

Detects over 70 bloodstream pathogens including rare and emerging threats

Resistance Gene Detection

Full-genome analysis identifies antibiotic resistance mechanisms

High Sensitivity

Detects low-level pathogens and unculturable organisms

Co-Infection Detection

Identifies multiple concurrent bloodstream infections

Automated Workflow

Compatible with automated platforms for consistent high-throughput testing

Fast Turnaround

Results within 24 hours for rapid clinical decision making

REFERENCES

References

Key literature supporting the development and evaluation of the blood pathogen panels.

Van CP et al. Invasive meningococcal disease remains a health threat in Vietnam People’s Army. 2021:5261–5269.
Lee D et al. Clinical evaluation of a loop-mediated isothermal amplification (LAMP) assay for rapid detection of Neisseria meningitidis in cerebrospinal fluid. 2015;10(4):e0122922.
W. Mason, G. Seal, J. Summers. Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus. J. Virol., 36 (1980), pp. 829-836.
C. Lauber, S. Seitz, S. Mattei, A. Suh, J. Beck, J. Herstein, et al. Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses. Cell Host Microbe., 22 (2017), pp. 387-399.e6.
R.C. Hirsch, J.E. Lavine, L.-J. Chang, H.E. Varmus, D. Ganem. Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription. Nature, 344 (1990), pp. 552-555.
M.A. Mendenhall, X. Hong, J. Hu. Hepatitis B virus capsid: the core in productive entry and covalently closed circular DNA formation. Viruses, 15 (2023), p. 642.
Y. Zhu, T. Yamamoto, J. Cullen, J. Saputelli, C.E. Aldrich, D.S. Miller, et al. Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J. Virol., 75 (2001), pp. 311-322.
M.S. Khuroo. Study of an epidemic of non-A, non-B hepatitis. Possibility of another human hepatitis virus distinct from post-transfusion non-A, non-B type. Am J Med, 68 (1980), Article A29, 10.1016/0002-9343(80)90194-1.
G. Di Cola, G. Di Cola, A. Fantilli, et al. High circulation of hepatitis E virus (HEV) in pigs from the central region of Argentina without evidence of virus occurrence in pork meat and derived products. Res Vet Sci, 164 (2023), Article 105000, 10.1016/j.rvsc.2023.105000.