200+
Pathogen Species
81M+
Capture Probes
99%+
Genome Coverage
1000x
Enrichment Factor

Probe Design

Probe design schematic
Optimized probe tiling strategy

We design high-coverage probes based on all polymorphic sequences of the target pathogen. Using sequence-similarity analysis, redundant probes in conserved regions are removed while preserving probe diversity in highly variable regions, ensuring comprehensive coverage with controlled cost.

Whole-Genome Capture Workflow for Pathogenic Microorganisms

DNA Work Flow
DNA Work Flow
RNA Work Flow
RNA Work Flow

Product Advantages

Broad Sample Compatibility — No Culturing Required

Supports a wide range of raw sample types including wastewater, human-derived samples (oral swabs, blood, urine, cerebrospinal fluid, etc.), and environmental specimens. No pre-culturing or host-depletion steps are needed, greatly simplifying preprocessing and significantly improving testing throughput.

Broad Strain Coverage — Complete, Reliable Data

Using efficient probe hybridization capture and enrichment, we achieve accurate, unbiased genomic identification—covering diverse pathogenic strains such as Influenza A, B and C; Norovirus genogroups I–V; and over 220 common HPV subtypes.

Excellent Sensitivity — Capture Low-Level Signals

By optimizing probes for low-abundance infections, we enable efficient binding and enrichment of target sequences. Pathogen nucleic acids with Ct ≤ 32 can be stably captured, laying a solid foundation for downstream high-sensitivity detection.

Performance Metrics

Key metrics demonstrating mapping and coverage performance

Total Reads Mapping Rate
Coverage Rate
T50% × Coverage Rate

Comprehensive Pathogen Coverage

Our flagship ABX panel covers the most clinically relevant pathogens across all major categories

Category Species Count Key Examples Coverage
Bacteria 64 species Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Mycobacterium tuberculosis 99%+
Viruses 88 species Influenza A/B, RSV, SARS-CoV-2, CMV, EBV, HSV-1/2 99%+
Fungi 5 species Candida spp., Aspergillus spp., Cryptococcus, Pneumocystis 99%+
AMR Genes 200+ genes mecA, vanA/B, KPC, NDM, CTX-M, mcr-1 Full length

Technical Details

Sample Types

Blood, BALF, sputum, CSF, tissue, swabs, urine, stool, and more

Input Requirements

100-500 ng DNA/RNA library input for optimal capture efficiency

Turnaround Time

4-hour hybridization protocol for rapid results

Platform Compatible

Illumina (NovaSeq, NextSeq, MiSeq) and MGI platforms

Sequencing Depth

Recommended 10-50M reads per sample for comprehensive analysis

Automation Ready

Compatible with IGT-AS01, AS12, and AS96 workstations

Ready to Capture More?

Contact our team to discuss which panel is right for your application