Zoonosis Related Pathogens Panel

BACKGROUND

Product Overview

Zoonotic pathogens are microorganisms that circulate and transmit within animal hosts and can cross species barriers to infect humans through multiple routes, including direct contact, bites, body fluids, foodborne exposure, and arthropod vectors. In their natural hosts, these pathogens are often associated with asymptomatic or inapparent infections; however, once introduced into humans, they may cause disease ranging from mild, self-limiting illness to severe, life-threatening infections—posing major challenges to public health security.

Leveraging iGeneTech’s proprietary TargetSeq® liquid-phase probe hybridization capture technology and a unique microbial probe design strategy, we focus on key challenges such as viral variant surveillance, detection of low-abundance viral samples, and host-source tracing. A portfolio of whole-genome detection kits for zoonotic (One Health) pathogens has been released to support comprehensive surveillance and research needs.

PRODUCT LIST

Comprehensive Zoonosis Related Pathogens Detection Panels

Complete portfolio of targeted panels for specific zoonosis-related pathogens.

Product Name	English Name	Taxonomy ID	Reference Genome Size	Reference Sequence Number	Number Of Probe
Streptococcus Suis Panel	Streptococcus suis	1307	2.2 Mb	191	348742
Leptospira Panel	Leptospira	171	4.0 Mb	166	1489132
Erysipelothrix Rhusiopathiae Panel	Erysipelothrix rhusiopathiae	1648	1.8 Mb	19	78151
Francisella Tularensis Panel	Francisella tularensis	263	1.9 Mb	80	78506
Rhodococcus Equi Panel	Rhodococcus equi	43767	5.4 Mb	26	240701
Streptobacillus Moniliformis Panel	Streptobacillus moniliformis	34105	1.7 Mb	3	54848
Pasteurella Multocida Panel	Pasteurella multocida	747	2.3 Mb	397	207108
Yersinia Pseudotuberculosis Panel	Yersinia pseudotuberculosis	633	4.6 Mb	40	218133
Brucella Panel	Brucella	234	3.3 Mb	387	903979
Bacillus Anthracis Panel	Bacillus anthracis	1392	5.5 Mb	158	241005
Mammarenavirus Panel	Mammarenavirus	1653394	-	483	82884

PERFORMANCE

Performance — Measured Results

Measured capture performance charts for representative zoonosis-related pathogen panels.

ORDERING INFO

Ordering Information — Catalog & Pack Sizes

Catalog numbers and available kit sizes for the listed panels.

Product Name	16 rxn	96 rxn
Streptococcus Suis Panel	PH2013471	PH2013472
Leptospira Panel	PH2013441	PH2013442
Erysipelothrix Rhusiopathiae Panel	PH2013101	PH2013102
Francisella Tularensis Panel	PH2013111	PH2013112
Rhodococcus Equi Panel	PH2013201	PH2013202
Streptobacillus Moniliformis Panel	PH2013231	PH2013232
Pasteurella Multocida Panel	PH2013161	PH2013162
Yersinia Pseudotuberculosis Panel	PH2013271	PH2013272
Brucella Panel	PH2013341	PH2013342
Bacillus Anthracis Panel	PH2014011	PH2014012
Mammarenavirus Panel	PH2014991	PH2014992

PANEL OVERVIEW

Comprehensive Zoonotic Pathogen Detection

The Zoonosis Related Pathogens Panel enables simultaneous detection and identification of over 75 zoonotic pathogens from a single sample, covering viruses, bacteria, parasites, and fungi transmitted from animals to humans.

Broad Host Range

Targets pathogens from mammals, birds, reptiles, and arthropod vectors

Multi-Pathogen Types

Detects viruses, bacteria, parasites, and fungi causing zoonotic diseases

Emerging Zoonoses

Includes high-priority emerging and re-emerging zoonotic pathogens

One Health Approach

Supports integrated human, animal, and environmental health surveillance

KEY ADVANTAGES

Why Choose OmniCapture Zoonosis Panel

Advanced technology for zoonotic pathogen detection

Multi-Host Coverage

Detects zoonotic pathogens from wildlife, livestock, and companion animals

All Pathogen Types

Comprehensive detection of viral, bacterial, parasitic, and fungal zoonoses

Emerging Pathogens

Includes high-priority emerging infectious disease agents

Genome Analysis

Full-genome sequencing for molecular epidemiology and source tracking

High Sensitivity

Detects low-level infections critical for early detection

One Health Support

Enables integrated human, animal, and environmental health surveillance

REFERENCES

References

Selected literature supporting targeted capture sequencing and infectious disease research.

Yu F, Ma N, Zhang X, et al. Comprehensive investigating of cytokine and receptor related genes variants in patients with chronic hepatitis B virus infection. Cytokine. 2018 Mar;103:10-14.
Pang X, Ren L, et al. Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing. Natl Sci Rev. 2020 Oct 23;7(12):1861-1864.
Du P, Ding N, et al. Genomic surveillance of COVID-19 cases in Beijing. Nat Commun. 2020 Oct 30;11(1):5503.
Chen C, Li J, et al. MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples. Mol Cell. 2020 Dec 17;80(6):1123-1134.e4.
Xu Y, Kang L, et al. Dynamics of severe acute respiratory syndrome coronavirus 2 genome variants in the feces during convalescence. J Genet Genomics. 2020 Oct 20;47(10):610-617.
Wu X, Ning C, et al. A 3,000-year-old, basal S. enterica lineage from Bronze Age Xinjiang suggests spread along the Proto-Silk Road. PLoS Pathog. 2021 Sep 21;17(9):e1009886.
Zhang J, Ding N, et al. Phylogenomic tracing of asymptomatic transmission in a COVID-19 outbreak. Innovation (Camb). 2021 May 28;2(2):100099.
Li J, Du P, et al. Two-step fitness selection for intra-host variations in SARS-CoV-2. Cell Rep. 2022 Jan 11;38(2):110205.
Song S, Li C, et al. Genomic Epidemiology of SARS-CoV-2 in Pakistan. Genomics Proteomics Bioinformatics. 2021 Oct;19(5):727-740.
Zhang J, Tian X, et al. Feasibility and Accuracy of Menstrual Blood Testing for High-risk Human Papillomavirus Detection With Capture Sequencing. JAMA Netw Open. 2021 Dec 1;4(12):e2140644.
Li P, Ke Y, et al. Targeted screening of genetic associations with COVID-19 susceptibility and severity. Front Genet. 2022 Nov 30;13:1073880.
Pu R, Liu W, et al. The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hapatocellular Carcinoma. Front Oncol. 2022 Feb 10;12:836517.
Zhang M, Zhang H, et al. Liver biopsy of chronic hepatitis B patients indicates HBV integration profile may complicate the endpoint and effect of entecavir treatment. Antiviral Res. 2022 Aug;204:105363.
Shen C, Li Y, et al. HTLV-1 infection of donor-derived T cells might promote acute graft-versus-host disease following liver transplantation. Nat Commun. 2022 Nov 30;13(1):7368.
Liu W, Cai S, et al. HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling. Cancers (Basel). 2022 Jul 4;14(13):3274.
Feng XL, Yu D, et al. Characteristics of replication and pathogenicity of SARS-CoV-2 Alpha and Delta isolates. Virol Sin. 2022 Dec;37(6):804-812.
Wang Y, Nan X, et al. Consumption of Supplementary Inulin Modulates Milk Microbiota and Metabolites in Dairy Cows with Subclinical Mastitis. Appl Environ Microbiol. 2022 Feb 22;88(4):e0205921.
Lang B, Cao C, et al. Genomic alterations related to HPV infection status in a cohort of Chinese prostate cancer patients. Eur J Med Res. 2023 Jul 17;28(1):239.
Adeola AC, Luka PD, et al. Target capture sequencing for the first Nigerian genotype I ASFV genome. Microb Genom. 2023 Jul;9(7):mgen001069.
Sun B, Andrades Valtueña A, et al. Origin and dispersal history of Hepatitis B virus in Eastern Eurasia. Nat Commun. 2024 Apr 5;15(1):2951.
Wang Z, Liu C, et al. Long-read sequencing reveals the structural complexity of genomic integration of HPV DNA in cervical cancer cell lines. BMC Genomics. 2024 Feb 20;25(1):198.
Yang Z, Zeng J, et al. Detection of HBV DNA integration in plasma cell-free DNA of different HBV diseases utilizing DNA capture strategy. Virol Sin. 2024 Aug;39(4):655-666.